منابع مشابه
By Philip J . Morrissey , David Bradley
Self-recognition and self-tolerance are two characteristics of the receptor repertoire expressed by functionally reactive T cells. Both of these facets of the T cell receptor repertoire are importantly influenced by the environment in which immature T cell precursors differentiate. For example, T cells specifically recognize as self the major histocompatibility complex (MHC)l-encoded determinan...
متن کاملPhilip J. Fay (1953-2014).
Philip J. Fay, Ph.D., Professor of Biochemistry and Biophysics at the University of Rochester, passed away on June 25, 2014 at the age of 61. He succumbed to the multiple myeloma that he had battled valiantly for 6 years. Phil is survived by his wife of 38 years, Andrea, daughters Amber and Emily, and five grandchildren. On July 8th the flags at the University of Rochester were lowered in his h...
متن کاملProfile of David J. Mangelsdorf.
T wo decades ago, David Mangelsdorf did not expect his basic research findings to help launch an entire field of biology with farreaching implications for a raft of human diseases, including cancer, metabolic disorders, and parasitic infections. Mangelsdorf, a Howard Hughes Medical Institute investigator and a professor of pharmacology at the University of Texas Southwestern Medical Center at D...
متن کاملDavid J. Gross - Nobel Lecture
The progress of science is much more muddled than is depicted in most history books. This is especially true of theoretical physics, partly because history is written by the victorious. Consequently, historians of science often ignore the many alternate paths that people wandered down, the many false clues they followed, the many misconceptions they had. These alternate points of view are less ...
متن کاملBy Stanley J . Korsmeyer , Philip a . Hieter ,
The maturation of a pre-B cell to an immunoglobulin (Ig)-bearing B cell requires an effective recombination of a light chain variable (VL) 1 and joining (JL) gene segment (1-11). Man uses both light chain gene classes appreciably, expressing K light chain in -60% and ~ light chain in 40% of mature B cells. Despite their nearly equal usage, however, the rearrangement of human Ig light chain gene...
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ژورنال
عنوان ژورنال: The American Journal of Theology
سال: 1898
ISSN: 1550-3283
DOI: 10.1086/476874